Efrim Waite also underwent an early test of some kind, though clearly they weren’t the “first human test subject” as is claimed. The direct effects on them aren’t mentioned and were probably not as severe (barring recent events):
Waite’s involvement with Sanial was heavily publicised when they volunteered to be the first human test subject for a neural colloid implant. In several interviews, Waite has expressed the belief that colloids are a highly beneficial technological development, stating that “colloids, rather than interstellar travel, are mankind’s only chance to see what lies beyond the primeval muck.” [3]
Not anything new, but the levels of depravity can be surprising sometimes!